Therapy Discovery

Innovation in therapeutic strategies.

We develop advanced models of disease and use our expertise in genetic and drug screens, cell biology, chemical biology, gene therapy, pathology and medicinal chemistry to discover targets and develop new drugs, with a view towards innovative therapeutic strategies.

Theme Lead: Professor Liz Patton

Colorectal Cancer Pathology

Proteostasis and Immune Signalling in Cancer and Dementia

Bioimage analysis and digital pathology

Development of pulmonary gene therapy approaches to treat cystic fibrosis and other genetic diseases

Signalling and the regulation of cancer growth and metastasis

Metabolism and Energy Signalling in Colorectal Cancer

Adhesion networks in cancer

Molecular Cancer Pathology

Next Generation Technologies for Drug Discovery In Cancer

Colorectal Stem Cell Transformation​

Discovery and clinical melanoma research to advance therapies and care for human and veterinary melanoma patients.

Tumour Immune Environment

NF-kB - Nucleolar Signalling

Innovative Therapeutics

Genome editing and targeted protein degradation