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Development of pulmonary gene therapy approaches to treat cystic fibrosis and other genetic diseases
High performance algorithms to analyse large and distributed datasets
A family and population based cohort study for research into the genetic, environmental and sociodemographic influences on health over the life-course
Uncovering the causes of consequences of inflammatory bowel disease by studying the role of genes, the environment, diet and microbiota and their inter-relationships in gut health and disease
Mechanisms of establishment, regulation and differentiation of early mammalian lineages in vivo and in vitro
Discovery and clinical melanoma research to advance therapies and care for human and veterinary melanoma patients.
Provide external quality assessment and educational material for end to end genomic testing for laboratories and clinical genetics centres globally to promote good practice, standardisation and patient safety through Genomics Quality Assessment (GenQA).
Systemic Lupus Erythematosis patient observational studies, fatigue management research, interventional pharma led studies.
Translational and clinical aspects of osteoimmunology; osteoporosis pathogenesis and treatment
Cellular and Molecular Mechanisms of Tissue Repair and Regeneration
Examining cellular and circuit dysfunction associated with monogenic forms of autism and intellectual disability
Using genetic discoveries to identify the mechanisms of mental illness and resilience
Methods for molecular and genetic epidemiology, with applications in clinical prediction and personalised medicine.
Respiratory gene therapy. Preclinical large animal safety/efficacy studies
Identification of risk factors, disease processes and new treatments for common genetic disorders
Improving the care and understanding of gout, and exploring the pathogenesis of osteoporosis
Genomic and data science approaches to understanding the pathophysiology of bipolar disorder
Using statistical methods to answer questions on the pathogenesis, progression and treatment of disease.
Tools and capabilities for sharing, accessing and integrating multi-dimensional bioimaging and biomolecular data
The integration of human psychiatric neuroimaging with genetics (common and rare variants), epigenetics, and stem cell models, in the context of clinically-relevant research
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