Research Groups

Research to understand how our genome works and how changes in DNA influence human health and cause disease.

Genetic and Chromosomal Stability in Mammalian Germ Cells

Chromatin Regulators in Cancer

Spatial Organisation of the Human Genome

Functional Genomics of Complex Traits

Signalling in Tissue Repair and Cancer

RNA processing and gene regulation

High performance algorithms to analyse large and distributed datasets

Diabetes Medical Informatics and Epidemiology

Genetic disorders of human neurological and immune function

Mechanism and Regulation of Chromosome Replication

Evolutionary trajectories of structural variation in cancer

Chromatin Structure and Genome Integrity

Mechanisms for Microcephaly, Cancer and Autoinflammation

RNA Synthetic Biology

Gene Regulation in Human Craniofacial Development and Disease

Protein Variant Interpretation

Genetics of Cilia Biology

Mechanisms of establishment, regulation and differentiation of early mammalian lineages in vivo and in vitro

Discovery and clinical melanoma research to advance therapies and care for human and veterinary melanoma patients.

ME/CFS Disease Mechanisms

Origins and Impacts of Structural Mutations

Epigenetics in Human Disease

Mutagenesis and its Biomedical Impact

Understanding Human Complex Trait Variation

Mechanistic understanding of chromatinopathies

Biomedical Data Science

Genome editing and targeted protein degradation

Genome defence mechanisms

Translational genomics in critical illness

Targeted Causal Machine Learning for Population Biomedicine

Chromatin Biochemistry and Epigenetics

Colorectal Cancer, Genetic Susceptibility, Prevention

Cellular and Molecular Mechanisms of Tissue Repair and Regeneration

Causal Quantitative Cancer Biology and Population Genomics

Epigenetic Mechanisms in Development and Disease

Topology and Viscoelasticity of DNA and Genomes

Human Genetic Disorders of Insulin Action

From GWAS to function

Quantitative traits in health and disease