Nicola Murray Centre for Ovarian Cancer Research Image Professor Charlie Gourley - Chair of Medical Oncology and Honorary Consultant in Medical Oncology; Clinical Director, CRUK Scotland Centre; Director, Nicola Murray Centre for Ovarian Cancer Research\n Research in a Nutshell Ovarian cancer is the sixth most common cause of female cancer death in the UK. Until recently it has been treated as a single disease entity. There is now considerable evidence to demonstrate that ovarian cancers differ in their tissues of origin, their genetic abnormalities, their responsiveness to chemotherapy and the ultimate outcome for patients. We are investigating the biology of this disease at the interface between the laboratory and the clinic in order to generate findings that can be directly translated into patient benefit. We do this by characterising the molecular changes that occur in different ovarian cancers and determining how this affects their responsiveness to chemotherapy or novel biological agents Research ProgrammeNicola Murray Foundation Image Charlie Gourley Research Group (Left to right: Charlie Gourley, Mike Churchman, John Thomson, Ian Croy, Lorna Stillie, Ailsa Oswald, Sarah Taylor and Eve Merry). Image People Charlie GourleyPrincipal Investigator; Chair of Medical Oncology and Honorary Consultant in Medical Oncology; Clinical Director, CRUK Scotland Centre; Director, Nicola Murray Centre for Ovarian Cancer ResearchMike ChurchmanLab ManagerJessica LimECAT Clinical Research FellowJohn ThomsonResearch FellowIan CroyHistology TechnicianLorna StillieTRACC Programme MB-PhD studentAilsa OswaldAZ-CRUK TRACC Clinical Research Training FellowSarah TaylorResearch FellowEve MerryEdinburgh Clinical Academic Track (ECAT) Wellcome PhD fellowLaboratory CollaborationsRobb HollisIGC Langmuir Talent FellowMolecular Cancer PathologySimon HerringtonProfessor of Molecular PathologyEmily SouthworthPhD studentOvarian and breast cancer signalling groupSimon LangdonReaderTargeting developmental cell states in melanomaLiz PattonGroup Leader/Personal Chair of Chemical GeneticsClinical Informatics and Health Economics in CancerPeter HallSenior clinical lecturer in Cancer InformaticsGrant CameronDatabase assistantDavid MeltonEmeritus ProfessorContactCharlie.Gourley@ed.ac.ukPA: laura.wood@ed.ac.uk Charlie Gourley - Research Information CollaborationsInternational Consortium for Low-Grade Serous Ovarian Cancer (ICLC): The University of Texas M. D. Anderson Cancer Centre, Memorial Sloan Kettering Cancer Centre, Johns Hopkins University, The University of Sydney, The Westmead Institute for Medical Research, Centre Leon Berard, BC Cancer, part of Provincial Health Services Authority, University of Otago, and the University of EdinburghCancer Research-UK Scotland Centre, UK (Edinburgh and Glasgow Ovarian Cancer Group): Prof Owen Samson, Dr Patricia Roxburgh, Dr Ros Glasspool, Dr Seth Coffelt, Dr David Millan and Dr Gareth Bryson.Cancer Research-UK Scotland Centre/ Wellbeing of Women/Artios: Dr Patricia RoxburghStanford Women Cancer Centre, Stanford University. Stanford, California: Professor Amer KaramPeter MacCallum Cancer Centre, Melbourne, Australia: Professor Ian Campbell and Dr Kylie Gorringe.University of Sydney, Sydney, Australia: Professor Anna de Fazio.Netherlands Cancer Institute, Amsterdam, Netherlands: Dr Christianne Lok.The University of Texas MD Anderson Cancer Centre: Professor David M. Gershenson, MDPartners and FundersNicola Murray foundation: Charitable donationCancer Research UK: Core funding, research grants and PhD fellowships.Wellbeing of Women/Artios: Research GrantUniversity College London Clinical Trials Unit/Cancer Research-UK/Astra Zeneca: ICON9 clinical trial and related translational researchAstraZeneca/Scottish Chief Scientist Office/Scottish Genome Partnership: Research grant.Medannex Ltd: Research GrantTarget Ovarian Cancer: Research GrantScientific ThemesOvarian cancer genomics and transcriptomics, translational research This article was published on 2024-09-23
