Advancing integrated studies of molecular pathways to understand how genome stability and cellular mechanisms drive health and disease. Cell and Genome Biology brings together researchers investigating how molecular pathways shape genome stability, nuclear organisation, and cellular function. By integrating expertise in chromatin biology, RNA regulation, developmental processes, and DNA repair, we seek to uncover the fundamental mechanisms that maintain cellular identity and influence human health. Our work spans molecular discovery to disease modelling, using innovative technologies to dissect how disruption of genome function leads to cancer, developmental disorders, and other pathologies. Through collaborative, interdisciplinary research, Cell and Genome Biology aims to generate transformative insights into the molecular foundations of health and the causes of human disease.Theme Lead: Professor Nick Gilbert Ian Adams Research Group Genetic and Chromosomal Stability in Mammalian Germ Cells Nezha Benabdallah Research Group Chromatin Regulators in Cancer Wendy Bickmore Research Group Spatial Organisation of the Human Genome Gerry Brien Research Group Chromatin Biochemistry and Epigenetics Javier Caceres Research Group RNA processing and gene regulation Vincenzo D’Angiolella Research Group Ubiquitin signaling in brain cancer Tom Deegan Research Group Mechanism and Regulation of Chromosome Replication Noor Gammoh Research Group Brain Cancer Survival Pathways Nick Gilbert Research Group Chromatin Structure and Genome Integrity Andrew Jackson Research Group Mechanisms for Microcephaly, Cancer and Autoinflammation Hannah Long Research Group Gene Regulation in Human Craniofacial Development and Disease Jenny Nichols Research Group Mechanisms of establishment, regulation and differentiation of early mammalian lineages in vivo and in vitro Duncan Sproul Research Group Epigenetics in Human Disease Ansgar Zoch Research Group Genome defence mechanisms This article was published on 2026-01-05