Karen Taylor Research Group

Breast Cancer Translational Pathology Group

Dr Karen Taylor

Group Leader and Research Fellow

Contact details

Research in a Nutshell

Breast cancer remains a global health challenge with 7.8 million new cases annually. Despite advances in treatment and screening it remains the leading cause of female cancer death globally and in the UK. There remains an urgent need for precision medicine approaches to discover and validate novel prognostic and predictive patient stratification models which are key to future clinical trial design. 

Our research focuses on the development and validation of biomarkers, integrating multi-omic approaches and digital/AI-based pathology. To achieve this our research is based on a large curated breast cancer translational pathology biobank of multiple well-annotated phase 3 clinical trials, which allow us to transform large datasets in to clinically relevant predictions at an individual patient level.

People

NameRole
Karen TaylorGroup Leader and Research Fellow
Tammy PiperSenior Research Technician and Tissue Bank Manager
Monika SobolResearch Technician

Key Publications

Collaborations

  • Professor David Cameron, The University of Edinburgh
  • Professor Peter Hall, The University of Edinburgh
  • Professor Ian Kunkler, The University of Edinburgh
  • Dr Arran Turnbull, The University of Edinburgh
  • Professor Iain MacPherson, The University of Glasgow
  • Professor Rob Stein, University College London
  • Professor Daniel Rea, University of Birmingham
  • Professor Robert Hills, University of Oxford
  • Dr Roberto Salgado, Peter MacCallum Cancer Centre, Australia & ZAS Hospitals, Belgium
  • Dr Mattias Rantalainen, Karolinska Institute, Sweden

Partners and Funders

  • Breast Cancer Research Foundation
  • Swedish Research Council
  • NHS Lothian Charity

 

Scientific Themes

Breast cancer, Translational pathology, Biomarker validation, Personalised Medicine, Phase 3 clinical trials

Disease Areas

Breast cancer

Technology Expertise

Phase 3 clinical trial translational pathology biobanking, histopathology, digital pathology, transcriptomics, proteomics