Regional variation in chemotherapy treatment for breast cancer across Scotland has reduced significantly over the past 15 years, according to a new study: December 2021 Image The findings suggest that there is now limited inequalities in treatment across the majority of the country’s 14 health boards.Experts from the University of Edinburgh say this means patients across Scotland with breast cancer can have confidence that they will receive consistent access to good quality treatment.Sustained improvementChemotherapy has contributed to a sustained improvement in the survival rates of breast cancer patients over recent decades, experts say.The decision to undergo treatment should be weighed against the side effects, which can be severe, and it is not recommended for all patients, they say.An appropriate uptake among patients for whom it is recommended is considered a marker of a well-functioning healthcare system.Despite this, there is no consensus on what the correct rate of chemotherapy use should be, experts say. Wide variation may indicate good or poor quality care in some areas.Inequitable accessResearchers say variation can be caused by inequitable access, uneven organisational performance, or differences in clinical practice.The research team analysed data of almost 49,000 patients with surgically treated early breast cancer between 2001 and 2018 from the Scottish Cancer Registry.Patients were treated in 14 health boards in Scotland, which are grouped together into three regional cancer networks.They found that the variation of chemotherapy use between the cancer networks was within three percentage points by 2018. This is compared to 10 percentage points in 2007.Close collaborationExperts suggest this convergence in chemotherapy use can be attributed to close collaboration and joined-up guideline development between Scottish Cancer Centres.The team found a small number of outliers from the national average when analysing the individual health boards, and say more research needs to be done to understand the reasons for that disparity.Breast cancer patients face a difficult choice when weighing up the pros and cons of chemotherapy. They can now have confidence that the advice they are getting from their oncologist is of the same high quality wherever they are being treated in Scotland. We have shown that Scotland is leading globally in its rich healthcare data and in the ability of data science to translate analysis into useful research to the benefit of future patients.Dr Peter HallReader and Consultant Medical Oncologist at the University of EdinburghThe study was funded by the Scottish Chief Scientist’s Office. It appears in the ESMO Open journal.Related linksRead the journal article in ESMO OpenStudy medicine at the University of Edinburgh[Image credit: Helen King via Getty Images] Tags 2021 Publication date 20 Dec, 2021