Scientists and clinicians working together to beat cancer. Edinburgh Cancer Research is part of the Institute of Genetics and Cancer, however, in addition to scientists based at the IGC, our cancer research is carried out at other University of Edinburgh sites (our affiliates) or NHS Lothian locations. A broad spectrum of tumour types is studied by our investigators and we aspire to be world class in key themes, bringing innovation and unique twists to basic cancer science, drug development and clinical translation. Some areas studied by our researchers include:The state of the host: lifestyle, risk and preventionStem cells and the cancer nicheSignal transduction and biological mechanismsPhenomics Drug Discovery, incorporating advanced imaging, pathway profiling and novel informatics solutionsStratification for therapyClinical/translational emphasis is largely in colorectal cancer, women’s cancers (breast, ovarian and endometrial), and more recently in brain cancer, but we have also initiated new research programmes in three new cancer types: sarcoma, renal cancer and intrahepatic cholangiocarcinoma, a poorly researched cancer of unmet need. Mark Arends Research Group Colorectal Cancer Pathology Kathryn Ball Research Group Proteostasis and Immune Signalling in Cancer and Dementia Nezha Benabdallah Research Group Chromatin Regulators in Cancer Paul Brennan Research Group Brain Tumour Research Group Gerry Brien Research Group Chromatin Biochemistry and Epigenetics Ewan Brown Research Group Melanoma and Colorectal Cancer Val Brunton Research Group Signalling and the regulation of cancer growth and metastasis David Cameron Research Group Clinical Trials in Breast Cancer Neil Carragher Research Group Drug Discovery Sally Clive Research Group Colorectal cancer and Cancers of Unknown Primary Vincenzo D’Angiolella Research Group Ubiquitin signaling in brain cancer Farhat Din Research Group Metabolism and Energy Signalling in Colorectal Cancer Mike Dixon Research Group Edinburgh Breast Unit Research Group Malcolm Dunlop Research Group Colorectal Cancer, Genetic Susceptibility, Prevention Marie Fallon Research Group Edinburgh Palliative and Supportive Care Group (EPAS) Susan Farrington Research Group Colorectal Cancer Genetics Margaret Frame Research Group Adhesion networks in cancer Noor Gammoh Research Group Brain Cancer Survival Pathways Charlie Gourley Research Group Nicola Murray Centre for Ovarian Cancer Research Robin Grant Research Group Causes, Treatment and Management of Glioma Peter Hall Research Group Clinical Informatics and Health Economics in Cancer Larry Hayward Research Group Sarcoma and Breast Cancer Simon Herrington Research Group Molecular Cancer Pathology Robb Hollis Research Group Molecular defects in ovarian cancers Ted Hupp Research Group Next Generation Technologies for Drug Discovery In Cancer Ian Kunkler Research Group Clinical and Translational Studies of Breast Radiotherapy Barry Laird Research Group Improving the Care of Patients with Cancer Kevin Myant Research Group Colorectal Stem Cell Transformation Olga Oikonomidou Research Group Clinical Translational Research in Breast Cancer Steven Pollard Research Group Neural Stem Cells and Brain Cancer Bin-Zhi Qian Research Group Tumour Microenvironment in Cancer Metastasis and Therapy Resistance Alan Serrels Research Group Tumour Immune Environment Dirk Sieger Research Group In Vivo Studies of Microglia-glioma Interactions Duncan Sproul Research Group Epigenetics in Human Disease Lesley Stark Research Group NF-kB - Nucleolar Signalling Stefan Symeonides Research Group Drug Development and Early Phase Cancer Trials Evropi Theodoratou Research Group Colorectal Cancer Epidemiology Arran Turnbull Research Group Translational Oncology Research Group – Breast Cancer Asier Unciti-Broceta Research Group Innovative Therapeutics Alexander von Kriegsheim Research Group Network Biology and Proteomics Simon Wilkinson Research Group Autophagy in Tissue Homeostasis and Cancer Tim Aitman Research Group Diagnosis of rare recessive disease by exome sequencing Ahsan Akram (Affiliate) Imaging in Lung Cancer for treatment stratification Linda Bauld (Affiliate) Public Health Luke Boulter Research Group Signalling in Tissue Repair and Cancer Hilary Critchley (Affiliate) Endometrial Biology and Menstrual Related Bleeding Complaints Andy Downes (Affiliate) Label-free Optical Spectroscopy and Imaging Elaine Dzierzak (Affiliate) Laboratory for Haematological Regeneration Sara Erridge (Affiliate) NHS Clinical Oncologist specialising in Neuro-Oncology Ailith Ewing Research Group Evolutionary trajectories of structural variation in cancer Yi Feng (Affiliate) Cancer prevention - in vivo models of tumour initiation Jonine Figueroa (Affiliate) Molecular Epidemiology of Cancer Stuart Forbes (Affiliate) Liver Regeneration and Cholangiocarcinoma Alison Hulme (Affiliate) Synthesis and Chemical Biology Katrin Ottersbach (Affiliate) Developmental Origins of Blood Stem Cells and Leukaemia Ava Khamseh Research Group Causal Quantitative Cancer Biology and Population Genomics Liz Patton Research Group Targeting developmental cell states in melanoma Philippa Saunders (Affiliate) Sex Steroid Hormone Action in Reproductive Health and Disease Gerry Thompson (Affiliate) Neuroimaging research Adam Waldman (Affiliate) Imaging Biomarkers in Adult Glioma Sarah Walmsley (Affiliate) Hypoxic regulation of neutrophilic inflammation This article was published on 2024-09-23
