Supervisor: Professor Andrew Jackson Our lab works on single gene human disorders with extreme phenotypes, including the smallest people in the world. As well as discovering new genes, we are interested in what these conditions can tell us about biological and common disease processes. To do so we use multiscale approaches including biochemistry, informatics, cell biology and animal models to discover new pathways and processes.We have made recent unpublished discoveries which link epigenetics and stem cell function with growth and ageing. We are developing cellular models to understand these links, and the mechanism by which DNA methylation alters stem cell output, that may shed light on stem cell plasticity, and exhaustion, with translational relevance to regenerative medicine. Andrew Jackson Research Group This article was published on 2025-11-07
