Our work spans Nature Metabolism, Nature Immunology, Nature Communications, Developmental Cell, and more. Read recent publications enabled by the facility, and hear what collaborators say about working with us.
Our facility is embedded in active research — not just a service unit. The team publishes extensively and our analytical work underpins discoveries across cancer biology, immunology, metabolism, and beyond.
16,700+ citations | h-index 52 | 180+ publications
View full publication list on Google Scholar
Selected Recent Publications (2025–2026)
These papers were enabled in whole or in part by analysis performed in the facility.
Proteomics
SOX2 phosphorylation during mitosis limits genomic damage
Williams et al., Genes & Development, 2026
Phosphoproteomic analysis mapping SOX2 PTMs during cell division.
Hypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity
Sanchez-Garcia et al., Nature Immunology, 2025
Deep proteomics and PTM analysis in primary immune cells under hypoxic stress.
An inherited mitochondrial DNA mutation remodels inflammatory cytokine responses in macrophages and in vivo in mice
Marques et al., Nature Communications, 2025
Proteomics linking mitochondrial genetics to immune cell phenotype.
ER-phagy and proteostasis defects prime pancreatic epithelial state changes in KRAS-mediated oncogenesis
Salomó Coll et al., Developmental Cell, 2025
Proteomics and multiomics in pancreatic cancer initiation.
Single-Cell & Spatial Proteomics
A Context-Aware Single-Cell Proteomics Analysis Pipeline (CASPA)
Salomó Coll, Makar et al., bioRxiv, 2026
Introducing CASPA — our in-house pipeline for cell-type annotation and biological interpretation of single-cell proteomics data. Open source: github.com/vonkriegsheim/CASPA
Artificial Intelligence-Driven Laser Capture Microdissection
Gasparello, Pearson, von Kriegsheim, Laser Capture Microdissection: Methods and Protocols, 2026
Integrating AI-guided LMD with deep visual proteomics workflows.
Metabolomics
Tumour sampling conditions perturb the metabolic landscape of clear cell renal cell carcinoma
Yong et al., Nature Communications, 2025
Metabolomic profiling of clinical tumour samples with implications for biomarker discovery.
FAK modulates glioblastoma stem cell energetics via regulation of glycolysis and glutamine oxidation
Masalmeh et al., Disease Models & Mechanisms, 2025
Targeted metabolomics tracing energy pathway rewiring in glioblastoma.
Lipidomics
Tissue-specific fibroblast lipid cues impose the rate of epithelial cancer invasion
Budden et al., Nature Metabolism, 2026
Lipidomic profiling revealing how stromal lipid signals drive tumour invasion.
The lipid transfer protein STARD7 controls intestinal tumor development in a context-dependent manner
Shostak et al., EMBO Molecular Medicine, 2026
Structural lipidomics in a mouse model of colorectal cancer.
Stay Up to Date
Follow our latest work on Google Scholar.
For enquiries about collaborative projects or using our services: mass-spec@igc.ed.ac.uk
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