How to Work With Us

Consultation, quote, sample submission, analysis, and data delivery — all explained. Includes answers to frequently asked questions: what samples we accept, how to prepare them, what you receive, and typical turnaround times.

We work with academic labs, clinical researchers, and industry partners — from initial experimental design through to fully interpreted results. Whether you have a clear project in mind or are unsure where to start, get in touch and we will help you design the right approach.

The Process

1. Consultation

Book a free consultation with a facility scientist. We will help you define the right experimental approach — whether that is a single omics pillar or an integrated multiomics strategy. We can advise on sample requirements, study design, and statistical power before you commit any samples.

Email us at mass-spec@igc.ed.ac.uk to arrange a consultation.

2. Project Submission & Quote

Submit your project via PPMS. We will provide transparent costing within a few working days. Internal Edinburgh collaborative rates apply for UoE researchers; external academic and industry quotes are provided on request.

3. Sample Preparation & Submission

We provide optimised sample preparation protocols for all sample types — follow these carefully to protect sample integrity and maximise data quality. See our Resources and Downloads page for submission guidelines and prep protocols.

4. Analysis

We run your samples on the appropriate high-resolution instruments. Your samples are tracked throughout, and we will contact you if any QC issues arise before analysis is complete.

5. Data Delivery

You receive a complete data package within approximately 2 weeks of sample receipt for standard projects. Larger or more complex projects are scoped at the consultation stage.

What You Receive

Every project includes a full delivery package — not just raw files:

  • Raw instrument data files (mzML / vendor format)
  • QC report — chromatographic performance, depth of coverage, reproducibility metrics
  • Processed quantitative data matrix — normalised and ready for downstream use
  • Differential expression (DE) analysis — results with fold-change and statistical significance
  • Visualisations — volcano plots, heatmaps, PCA
  • Pathway analysis — GSEA, GO enrichment, GSVA
  • Single-cell proteomics projects additionally include cell-type annotation using CASPA, our in-house analysis pipeline

We don't hand back files and leave you to figure it out — the data package is designed so you can go directly to biological interpretation.

 

Collage of data output
Output from a supervised (grouped) data analysis

Frequently Asked Questions

What sample types do you accept?

We work with tissues (FFPE and fresh/frozen), biological fluids (serum, plasma, urine, CSF, etc.), and cells (cell lines, primary cells, sorted populations, single cells). If you are unsure whether your sample type is suitable, email us — we are happy to advise.

How little sample do I need?

Very little. Our integrated multiomics workflow is specifically designed for precious or low-input samples — we can extract and analyse proteins, metabolites, and lipids from a single sample, even down to a single cell for proteomics. Tell us about your sample constraints in the consultation and we will design the workflow accordingly.

Can you work with FFPE material?

Yes. Our Deep Visual Proteomics (DVP) workflow uses laser microdissection (Leica LMD7) to capture specific cell populations or regions of interest directly from FFPE or fresh tissue sections. This is a specialist capability — see our Services and Expertise page for more detail.

How should I prepare my samples?

Download our sample preparation protocols from the Resources and Downloads page. Following these protocols carefully is important: improper storage or freeze-thaw cycles can significantly affect data quality, particularly for metabolomics and lipidomics. If in doubt, contact us before you process your samples.

How long does analysis take?

We aim for a 2-week turnaround from sample receipt for standard projects. Complex or large-cohort projects will have timelines agreed at the consultation stage.

What bioinformatics analysis is included?

Full downstream analysis is included in the service cost — differential expression, GSEA, GO enrichment, GSVA, and pathway visualisations. For single-cell proteomics, cell-type annotation is performed using CASPA, our in-house open-source pipeline. You do not need your own bioinformatics resource to use our facility.

Can we collaborate rather than just use it as a service?

Yes. Many projects run as genuine collaborations, with facility scientists contributing to experimental design, data interpretation, and co-authorship. If you are interested in a deeper collaboration, mention this at the consultation stage.

I am from industry — can I still use the facility?

Yes. We welcome industrial partnerships and operate a fee-for-service model for non-academic clients. Contact us for a bespoke quote.

Pricing Summary

ServiceCollaborative Rate
Bulk Proteomics£50–£100 per sample
Metabolomics (Semi-targeted)£50 per sample
Lipidomics (Untargeted)£50 per sample
Spatial Proteomics / DVP£50 per ROI
Single-Cell Proteomics~£30 per cell (>100 cells)

Full pricing detail and industry/external academic rates: see Pricing and Access.

Get in Touch

Email: mass-spec@igc.ed.ac.uk
Book via PPMS: https://ppms.eu/igmm/?igcms