Cancer Research UK have been funding our research to study the genetic architecture of colorectal cancer for some time. Image Cancer Research UK have been funding our research to study the genetic architecture of colorectal cancer for some time. We are now entering a new phase and The SCOTTY Study forms part of that endeavour. We aim to recruit trios (Patients & Parents) of early onset colorectal cancer in whom there is no known family history, and known alleles have been excluded as best as is possible. Whilst cancer of the large bowel is common, it is very rare in young people under the age of 40. Our aim in this study is to look at samples (blood and tissue removed from tumours) from individuals who have developed bowel cancer at a young age and also blood samples from each of their parents. These samples will be analysed using a technique called “Next-Generation Sequencing” (NGS). NGS is a scientific technique that gives us a “read-out” of all the genetic information that is stored in our DNA within each of our cells within the body. It is this information that makes every person unique. In doing this and comparing your sample to those of your parents, we aim to identify changes in your DNA (mutations) that are not present in your parents. We aim to collect this information to help us identify mutations that are causing bowel cancer. This will in the long term help us to develop new treatments and predict who will be susceptible to cancer and so be able to prevent disease progression. Please follow the links below for more detailed information on the study. If you would like to discuss this further, are interested in participating or have any questions, please contact us. Donna Markie, our Senior Research Nurse & Study Coordinator can be contacted on: Telephone: +44 (0)131 651 8602 Email: Donna.Markie@ed.ac.uk You can also get in touch with us through our social media channels. Best wishes, The SCOTTY Team Facebook Twitter scottystudy@ed.ac.uk This article was published on 2024-09-23
